EN|FR
Discover
Features

LabGiant,

Already have an account?

LabGiant,

Features

Equipment CalendarProtocol CortexCRMImpact Reporting

Explore

Research IndexTechniquesCommunityPlans

In partnership with

McGill UniversityConcordia UniversityUniversité de MontréalPolytechnique MontréalDobson Centre for EntrepreneurshipUniversity of Alberta
© 2026 LabGiant
EN|FR
Privacy PolicyTerms of Service
    Protocol Cortex

    Your best people are leaving.
    Their protocols keep getting sharper.

    When a researcher improves a protocol, they propose the change with the supporting papers already pulled for you. You review and merge, the credit stays with them, and your lab's expertise compounds instead of walking out the door.

    Describe a protocol. AI writes the draft. Free to start.

    Sarah proposes changes to your lab template. You review the diff and decide.

    Western Blot - StandardSubmitted by Sarah Chen for your review
    Analysis completeMerges into your lab template

    Summary Substitutes BSA with non-fat milk for improved blocking. Extends incubation and wash cycles. 3 literature sources.

    3 units·10 changes·Low risk·Ready to apply·Literature-backed reagent substitution with linked incubation changes
    Change Units
    Current Template
    Proposed Changes
    Reagent Substitution
    2
    Linked3 sources

    Why linked: BSA-to-milk swap requires adjusted incubation for optimal blocking.

    Chen 2022Park 2021BioProtocol
    Risk: LOWAccepted
    Phase 2Blocking
    60 min
    1
    Block membrane with 5% BSA in TBS-T
    2
    Incubate for 1 hour at room temperature
    3
    Do not let membrane dry during incubation
    Phase 2Blocking
    120 min
    1
    Block membrane with 5% non-fat milk in TBS-T
    2
    Incubate for 2 hours at room temperature
    3
    Do not let membrane dry during incubation
    Chen, R. et al. (2022)J. Immunological MethodsVerified847 citations

    Key finding: 40% lower background signal with non-fat milk vs BSA across 6 antibody-antigen pairs.

    View
    Wash Optimization
    4
    Linked2 sources
    Accepted
    Phase 3Washing
    15 min
    1
    Wash 3x with TBS-T, 5 min each
    2
    Rock membrane at 15 rpm on platform shaker
    3
    Decant buffer between washes without touching membrane
    4
    Ensure complete removal of blocking agent
    5
    Rinse once with TBST before next phase
    6
    Blot excess liquid from membrane edge on filter paper
    Phase 3Washing
    50 min
    1
    Wash 5x with TBS-T, 10 min each
    2
    Rock membrane at 25 rpm on platform shaker
    3
    Decant buffer between washes without touching membrane
    4
    Ensure complete removal of blocking agent
    5
    Rinse twice with TBST before next phase
    6
    Blot excess liquid from membrane edge on filter paper
    Temperature Adjustment
    3
    Independent1 source
    Click to review
    Phase 4Primary Antibody
    12 hours
    1
    Incubate at 4°C overnight
    2
    Dilute primary 1:1000 in 5% BSA/TBST
    3
    Use minimal volume to cover membrane evenly
    4
    Protect from light
    5
    Do not add sodium azide to antibody buffer
    6
    Store plate wrapped in foil at 4°C until imaging
    Phase 4Primary Antibody
    2 hours
    1
    Incubate at room temperature for 2 hours
    2
    Dilute primary 1:2000 in 5% milk/TBST
    3
    Use minimal volume to cover membrane evenly
    4
    Protect from light
    5
    Do not add sodium azide to antibody buffer
    6
    Discard primary antibody after single use

    Built for labs where protocols are living science, not static documents

    Propose and Merge

    Researchers propose improvements to lab templates. PIs review the diff. The best ideas get merged, credited to whoever proposed them. Like version control, but for science.

    AI-Powered Review

    Every proposal analyzed in three phases: structural diff, AI-generated insights, and literature citations that validate the change.

    Inventory on Autopilot

    Every protocol run deducts reagents automatically. Running low triggers a reorder. You never write a purchase request again.

    Full Version History

    Every optimization tracked. Every version recoverable. Complete audit trail of who changed what, when, and why.

    One protocol run. Four systems updated.

    Protocol Run: Western Blot v3.2Complete

    Reagents deducted. Reorders placed.

    BSA, TBS-T, non-fat milk. Every material listed in the protocol is deducted the moment the run completes. Drop below threshold? The reorder goes out before anyone notices.

    -250ml BSA

    Reagents deducted. Reorders placed.

    BSA, TBS-T, non-fat milk. Every material listed in the protocol is deducted the moment the run completes. Drop below threshold? The reorder goes out before anyone notices.

    -250ml BSA

    Next slot booked. Before you ask.

    The protocol needs 2 hours on the plate reader tomorrow. The system checks availability and holds the slot. Your grad student just confirms.

    2h reserved

    Next slot booked. Before you ask.

    The protocol needs 2 hours on the plate reader tomorrow. The system checks availability and holds the slot. Your grad student just confirms.

    2h reserved

    Every hour tracked. Every sample logged.

    Equipment hours, human hours, sample prep time. All captured per-project as the protocol runs. Not reconstructed from memory at billing time.

    3.5h tracked

    Every hour tracked. Every sample logged.

    Equipment hours, human hours, sample prep time. All captured per-project as the protocol runs. Not reconstructed from memory at billing time.

    3.5h tracked

    End of month. One click.

    Every protocol run tracked every resource. Generating the invoice is not a research project of its own. One button. Accurate to the reagent.

    Invoice ready

    End of month. One click.

    Every protocol run tracked every resource. Generating the invoice is not a research project of its own. One button. Accurate to the reagent.

    Invoice ready

    This is what happens when the protocol is the operating system.

    The invisible cost of disconnected tools

    How many hours does your lab spend reconciling inventory after protocol runs?

    How many equipment slots go unbooked because nobody checked the schedule?

    How many invoices are estimates instead of records?

    How much institutional knowledge left with your last graduating class?

    Protocol Cortex answers all of these. By making the protocol the source of truth.

    Your lab is already running protocols. Now make them run your lab.

    The labs already on this never rebuild from scratch again.

    Describe a protocol. AI writes the draft. Free to start.