The cheapest problem to fix is the one that has not happened yet. Bring us your question before you generate data and we will help you design a study that can answer it.

That means power analysis and sample size, the experimental design strategies that minimize technical variability, and the structure that keeps batch effects from becoming your finding. For repeated measures work, where the same cells, animals, or subjects are measured across conditions or time points, we use simulation-based power calculations under mixed-effects models rather than rules of thumb.

Useful whether you are preparing a grant application, planning a pilot, or building an analysis pipeline you want to hold up later.