This service performs transepithelial electrophysiological measurements on well-differentiated epithelial cells. These measurements are crucial for assessing ion transport across epithelial barriers, which is fundamental in understanding various physiological processes and disease mechanisms, particularly in respiratory diseases like Cystic Fibrosis. The service is offered on a fee-for-service basis for basic research and drug discovery projects. Electrophysiological measurements, often conducted using techniques like Ussing chambers, provide quantitative data on parameters such as transepithelial electrical resistance (TEER), short-circuit current (Isc), and potential difference, reflecting the integrity and function of tight junctions and ion channels. This service is particularly valuable for studying the effects of new therapeutic agents on epithelial function, including drug efficacy and toxicity, and for characterizing the transport properties of various compounds.