This service provides the cutting of prepared tissue blocks into ultra-thin sections for microscopic analysis. Two primary methods are offered: paraffin sectioning and frozen sectioning. Paraffin sectioning involves slicing paraffin-embedded tissue blocks using a microtome, typically yielding sections 4-10 micrometers thick. These sections are known for their physical stability, excellent tissue morphology preservation, and suitability for various staining techniques. Frozen sectioning (cryosectioning) involves cutting thin sections of rapidly frozen tissue using a cryostat. While physically less stable than paraffin sections, frozen sections are superior for preserving antigenicity and lipid retention, making them ideal for immunofluorescence and other applications where antigen integrity is crucial. Both methods are essential for detailed histological analysis in research and diagnostics.

Lady Davis Institute
Research lab focused on advancing scientific knowledge and innovation.
This service provides the cutting of prepared tissue blocks into ultra-thin sections for microscopic analysis. Two primary methods are offered: paraffin sectioning and frozen sectioning. Paraffin sectioning involves slicing paraffin-embedded tissue blocks using a microtome, typically yielding sections 4-10 micrometers thick. These sections are known for their physical stability, excellent tissue morphology preservation, and suitability for various staining techniques. Frozen sectioning (cryosectioning) involves cutting thin sections of rapidly frozen tissue using a cryostat. While physically less stable than paraffin sections, frozen sections are superior for preserving antigenicity and lipid retention, making them ideal for immunofluorescence and other applications where antigen integrity is crucial. Both methods are essential for detailed histological analysis in research and diagnostics.

Lady Davis Institute
Research lab focused on advancing scientific knowledge and innovation.
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