IMR-90 cells are a human fetal lung fibroblast cell line used in research to study cellular senescence, aging, and lung development. These cells have a finite lifespan in culture and are a valuable model for investigating the mechanisms regulating cellular aging., These cells are provided at varying quantities. They are typically cultured in a standard cell culture medium supplemented with serum and antibiotics. They are frequently used in studies of cell cycle regulation, DNA damage response, and extracellular matrix remodeling.