Overview

A compact, modular light‐scattering instrument that combines:

1. Dynamic Light Scattering (DLS) for particle/molecule size (0.3 nm – 10 µm)
2. Electrophoretic Light Scattering (ELS) for zeta potential (± 500 mV)

Models range from entry-level (Lab) to fully featured (Ultra with Multi-Angle DLS and concentration/MW analysis). All share the ZS Xplorer™ software platform and can be upgraded (e.g., titration, MW, concentration modules).

Key Features

1. Particle Size (DLS)
2. Range: 0.3 nm – 10 µm (aqueous; depends on refractive index/viscosity)
3. Backscatter (173°) plus selectable angles (13°, 90°) or simultaneous 3-angle (Ultra/MADLS®)
4. Adaptive correlation for dilute or low-scattering samples
5. Zeta Potential (ELS)
6. Range: ± 500 mV (voltage up to ± 150 V, sample conductivity 0.1 – 200 mS/cm)
7. M3-PALS phase-analysis mode with Fast/Slow Field Reversal
8. Automated quality checks (count rate, attenuator position)
9. Temperature Control
10. Standard Peltier: ambient + 4 °C – 90 °C (± 0.1 °C)
11. Optional low-temperature module: –10 °C – 90 °C
12. Rapid equilibration (< 5 min to ± 0.1 °C)
13. Modular Accessories
14. MADLS® (Ultra only): simultaneous 13°, 90°, 173° for high-resolution polydisperse samples
15. Particle Concentration (Ultra Red): 10⁶ – 10¹² particles/mL
16. Molecular Weight (Ultra): 10 kDa – 2 MDa via static light scattering
17. Autotitrator (MPT-3): automated pH titrations for size vs. pH or zeta vs. pH
18. Capillary Cells & Disposable Cuvettes: low-volume (50 µL), standard (3 mL), high-conductivity cells
19. Software (ZS Xplorer™)
20. Method templates (Size scan, Zeta scan, Concentration, MW analysis, Titration)
21. Real-time data-quality advice (alerts on poor count rates, incorrect concentration)
22. Export raw correlation functions, distributions, and histograms (CSV/Excel/LIMS)

Common Applications

1. Nanoparticle Characterization: liposomes, polymer/inorganic colloids, exosomes, virus-like particles.
2. Protein & Biologics: aggregation studies, isoelectric point, monomer vs. aggregate sizing.
3. Formulation R&D: emulsions, suspensions, surfactants, vaccine adjuvants.
4. Concentration & QC: rapid titering of viral particles, nanoparticle batch-to-batch consistency.
5. Polymer/Polymeric Micelle Analysis: molecular-weight determination, size distribution in solution.