Primary Function: A magnetic bead-based immunoassay instrument designed for rapid, accurate biomarker quantification using xMAP technology. This flow cytometry-based analyzer integrates advanced components to perform multiplexed assays, enabling simultaneous detection of multiple analytes from a single, small-volume sample.
Technical Capabilities: The Luminex 200 System is a robust and widely adopted platform for multiplexing, capable of performing up to 100 different tests in a single reaction volume. It offers high sensitivity and a broad dynamic range, making it suitable for a wide array of research and diagnostic applications.
Applications: Beyond general biomarker quantification, the system is extensively used for:
- Genomic and proteomics drug discovery, including single nucleotide polymorphism (SNP) and expression analysis.
- Diagnostic applications such as genetically inherited disease screening (e.g., cystic fibrosis), HLA typing for transplantation, autoimmune disease profiling, and molecular pathogen detection.
- Research assay applications including gene expression analysis, genotyping, protein expression analysis, animal-model serum analyte profiling, antibody epitope mapping, enzyme/substrate research, and protein-protein interaction analysis.
- High-throughput compound screening, kinase selectivity screening, serological studies, multianalyte drug and drug metabolite profiling, toxicology and drug metabolism studies, and drug target validation.
- Studies in immunology, cancer, veterinary medicine, metabolism/endocrinology, and neuroscience.
- Analysis of nucleic acid assays, receptor-ligand assays, immunoassays, and enzymatic assays.