This service focuses on generating Formalin-Fixed Paraffin-Embedded (FFPE) tissue curls, also known as shavings or scrolls. During this process, the paraffin-embedded tissue block is sliced into ultra-thin sections (typically 10 microns, but adjustable based on requirements) using a microtome. These thin, curled shavings are collected and are particularly valuable for downstream molecular analyses, such as DNA or RNA extraction, as they provide a convenient format for isolating nucleic acids from archived tissue samples. The process is meticulously performed to prevent cross-contamination, often involving cleaning of equipment and changing blades between samples.

Lady Davis Institute
Research lab focused on advancing scientific knowledge and innovation.
This service focuses on generating Formalin-Fixed Paraffin-Embedded (FFPE) tissue curls, also known as shavings or scrolls. During this process, the paraffin-embedded tissue block is sliced into ultra-thin sections (typically 10 microns, but adjustable based on requirements) using a microtome. These thin, curled shavings are collected and are particularly valuable for downstream molecular analyses, such as DNA or RNA extraction, as they provide a convenient format for isolating nucleic acids from archived tissue samples. The process is meticulously performed to prevent cross-contamination, often involving cleaning of equipment and changing blades between samples.

Lady Davis Institute
Research lab focused on advancing scientific knowledge and innovation.
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