CFBE cells are cystic fibrosis bronchial epithelial cells used as a model for studying cystic fibrosis transmembrane conductance regulator (CFTR) function and dysfunction. They are derived from human bronchial epithelial cells and retain the characteristic features of CF cells, including defective chloride transport., These cells are valuable tools for investigating the mechanisms underlying CFTR mutations and for developing and testing potential therapeutic interventions for cystic fibrosis. They are commonly used in electrophysiological studies, such as Ussing chamber experiments, to measure chloride transport across the cell membrane. Passage number and date of creation are provided for tracking and experimental reproducibility.