The Canadian Centre for Computational Genomics (C3G) offers comprehensive analysis services for microbiome and metagenomics studies, covering both amplicon-based and whole genome sequencing (WGS) approaches. These services enable researchers to explore microbial communities with high precision, from taxonomic classification to functional annotation.

For amplicon-based metagenomics (16S, 18S, ITS, COI), C3G provides a streamlined workflow that includes denoising of raw reads into Amplicon Sequence Variants (ASVs) using a dada2- or QIIME-based pipeline. Taxonomy assignment and functional annotation ensure that researchers can accurately characterize microbial communities. Deliverables are formatted for direct use with MicrobiomeAnalyst and Calypso, facilitating the creation of high-quality, publication-ready visualizations.

Beyond traditional metagenomics, C3G is at the forefront of metatranscriptomics innovation, offering cutting-edge RNA-Seq solutions to study active microbial communities. Their integrated pipelines allow for deep functional analysis, including the construction of KEGG global metabolic networks and co-occurrence networks from WGS and 16S data, providing insights into microbial interactions and ecosystem functions.