The Agilent Bioanalyzer Reagents Selection Guide is a critical digital document for users of the Agilent 2100 Bioanalyzer system, providing detailed specifications and recommendations for the various reagent kits available. This guide ensures that researchers select the most appropriate kit for their specific sample analysis needs, optimizing the performance of the Bioanalyzer. This comprehensive guide outlines the quantitative and qualitative ranges, sizing capabilities, sensitivity, and typical number of samples per kit for RNA, DNA, and protein analysis. It covers a wide array of kits, including RNA Nano and Pico kits for total RNA and mRNA analysis, Small RNA kits for microRNA and exosome-sized species, and various DNA kits (e.g., DNA 1000, 7500, 12000, High Sensitivity DNA) for fragment analysis. The guide is instrumental in helping researchers achieve accurate and reproducible results for applications such as RNA quality assessment, including the industry-standard RNA Integrity Number (RIN) values, DNA sizing and quantification, and protein purity and concentration determination. It aids in understanding the specific characteristics and limitations of each kit. Moreover, the selection guide often includes essential sample preparation guidelines, emphasizing the importance of sample purity and concentration for optimal Bioanalyzer performance. It serves as a valuable reference for maximizing the utility of the Agilent 2100 Bioanalyzer for on-chip electrophoresis and flow cytometry in genomics, proteomics, and molecular biology workflows.