The Mass Spectrometry Facility at the Centre for Research in Biopharmaceuticals and Biotechnology (CRBS) provides advanced mass spectrometry capabilities for protein identification, small molecule analysis, and metabolomics. Equipped with state-of-the-art instrumentation, this facility enables high-sensitivity detection, molecular characterization, and quantitative analysis of biomolecules.

Key Equipment & Capabilities:

• Bruker Microflex MALDI-TOF Mass Spectrometer
• Ideal for metabolite, small molecule, and small protein detection.
• Provides matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) analysis for high-throughput sample screening.
• Bruker Amazon Speed ETD Ion Trap Mass Spectrometer
• Supports liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis.
• Capable of intact protein mass determination and small molecule mass analysis.
• Features Electron Transfer Dissociation (ETD) for improved peptide and post-translational modification characterization.
• 1D Reverse-Phase HPLC Coupling
• Enhances mass spectrometry workflows by providing high-resolution separation of biomolecules before MS detection.
• Supports LC-MS/MS applications for complex sample mixtures.

This facility is essential for biopharmaceutical research, proteomics, and analytical chemistry, offering high-precision tools for molecular identification and characterization.

For McGill lab users, unsupervised access is available at $5/hour. Prior training and booking are required for equipment usage.