Custom NGS library preparation
The core is experienced in building libraries from diverse biological systems with varied methods, and tailors the preparation to the goal of your project: DNA and RNA-seq, SMART-seq, amplicon sequencing, PacBio SMRT sequencing, CRISPR-based single-cell screens and others.
You provide
- SamplesCells, nuclei, tissue or nucleic acid
- Sample QC, sample sheet or earlier data
Request this service
Genomics Core replies with scope and price.
Your details
Your lab
Find your lab
Join your lab to use its details for future bookings and requests.
Nothing is booked or charged until you accept a quote.
You receive
- Sequencing libraries built for your project
- A preparation method chosen for your project goals
How it goes
You ask
Answer a few questions about your samples.
They scope it
The facility confirms it can be done and may ask for a detail or two.
You accept a quote
Price and timing, agreed before any work starts.
Results come back
Files arrive in your requests, with a note from the facility.
Where it's been used
RNA-seq libraries from mouse embryonic stem cells becoming heart muscle cells, in a study of how BAF complex subunits shape heart gene programs.
Dynamic BAF chromatin remodeling complex subunit inclusion promotes temporally distinct gene expression programs in cardiogenesis
Hota, Johnson, Verschueren, et al. · Development · 2019
ChIP-seq and RNA-seq libraries, with QC, from mouse NIH3T3 cells, in a study of how acetylation of the RNA Pol II tail is read by RPRD proteins.
Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins
Ali, Ruiz, Ni, et al. · Molecular Cell · 2019
RNA-seq libraries from embryonic and newborn mouse hearts lacking Baf60c, in a study of a BAF subunit needed for heart development and function.
Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function
Sun, Hota, Zhou, et al. · Biology Open · 2017
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