10x Genomics single-cell assays
The core profiles gene expression and open chromatin at the single-cell level with 10x Genomics Chromium assays: 3' and 5' gene expression, V(D)J profiling, ATAC and Multiome, which reads ATAC and gene expression from the same nucleus.
The service runs from cell or nucleus partitioning through library construction to sequencing, with every QC check along the way.
You provide
- SamplesCells, nuclei, tissue or nucleic acid
- Sample QC, sample sheet or earlier data
Request this service
Genomics Core replies with scope and price.
Your details
Your lab
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Join your lab to use its details for future bookings and requests.
Nothing is booked or charged until you accept a quote.
You receive
- Cells or nuclei partitioned on the 10x Chromium
- Libraries built and checked at every step
- Sequencing data from your libraries
How it goes
You ask
Answer a few questions about your samples.
They scope it
The facility confirms it can be done and may ask for a detail or two.
You accept a quote
Price and timing, agreed before any work starts.
Results come back
Files arrive in your requests, with a note from the facility.
Where it's been used
10x single-cell and bulk RNA-seq libraries and sequencing of ROS-producing immune cells from mouse spinal cords, in a model of multiple sclerosis.
Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation
Mendiola, Ryu, Bardehle, et al. · Nature Immunology · 2020
10x Chromium single-cell RNA-seq of heart-forming regions from normal and Hand2-null mouse embryos at three early stages of heart development.
Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects
Soysa, Ranade, Okawa, et al. · Nature · 2019
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