iPS cell reprogramming
The core reprograms human iPS cells from peripheral blood mononuclear cells (PBMCs) or from human fibroblasts. When you start from whole blood, it isolates the PBMCs first.
You provide
- Starting materialPBMCs, human fibroblasts, whole blood, or an existing iPS cell line
- Protocol or earlier data
Request this service
Stem Cell Core replies with scope and price.
Your details
Your lab
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Nothing is booked or charged until you accept a quote.
You receive
- Human iPS cells from your donor's blood or fibroblasts
- PBMCs isolated from whole blood, when you start from blood
How it goes
You ask
Answer a few questions about your samples.
They scope it
The facility confirms it can be done and may ask for a detail or two.
You accept a quote
Price and timing, agreed before any work starts.
Results come back
Files arrive in your requests, with a note from the facility.
Where it's been used
Reprogramming of blood cells (PBMCs) from identical twins discordant for macular degeneration into a genetically matched pair of iPS cell lines.
Generation of induced pluripotent stem cell lines (RFSCi003-A, RFSCi004-A) from monozygotic twins discordant for age-related macular degeneration
Rajendran, Runyon, Hu, et al. · Stem Cell Research · 2025
iPS cell lines from a macular degeneration patient with hyperreflective foci and from an unaffected sibling, made with core staff.
Generation of human induced pluripotent stem cell lines from an age-related macular degeneration patient with hyperreflective foci overlying drusen (RFSCi002-A) and an unaffected sibling (RFSCi001-A)
Ashrafi, Runyon, Hu, et al. · Stem Cell Research · 2025
Patient iPS cell lines from a family with childhood-onset cardiomyopathy, turned into heart muscle cells to test how an NKX2-5 variant modifies the disease.
Oligogenic inheritance of a human heart disease involving a genetic modifier
Gifford, Ranade, Samarakoon, et al. · Science · 2019
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